Proprietary Work

Global Economic Dossiers
Formulary submission packages
Presentation materials
Recent briefing reports
Patient Information & Educational Materials (for example…)

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Global Economic Dossiers

Global dossiers to support the market access function, these synthesize relevant clinical and economic research, publicly accessible literature and market strategy and present an evidence-based value rationale. We have developed these for pipeline or approved products in a variety of therapeutic areas… cardiology, gastroenterology, infectious disease, neurology, oncology, psychiatry, rheumatology,…

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Formulary submission packages

Over 200 submissions to Canadian and US formulary decisionmakers prepared to date, including clinical and economic background and rationale, budget impact models and reports, product-specific and audience-specific forms and reports

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Presentation materials

Posters, slides, handouts, and other presentation materials for in-house or external dissemination of health outcomes information, research and strategy (Posters, Podiums and Keynote presentations, classroom or conference room materials)

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Backgrounders, Briefing Documents & Reports (for example…)

• Antithrombotic Therapy for Prevention of Stroke in Atrial Fibrillation: Evidence on Disease Burden and Unmet Needs
  
• Analysis of sub-optimal coagulation in atrial fibrillation
  
• Comprehensive literature review on the burden of disease and unmet needs for prevention and treatment of venous thromboembolism (VTE) in the medically ill
  
• The association between anal intraepithelial neoplasia (AIN) and anal cancer
  
• Atrial fibrillation patient subgroup analysis
  
• Costs of urinary tract infections in Germany, the UK and USA
  
• Role of HTA in decisionmaking: report on selected drug policy issues in Canada
  
• Aspects of the natural history of human papillomavirus (HPV) infection and associated diseases
  
• Systematic literature review on quality of life and ostomy
  
• Assessing the future of 'authorized generics' in different market segments - US, UK, France & Japan
  
• Renal anemia and EPO - Pre-dialysis renal anemia market
  
• Venous leg ulcers (all forms) - patient compliance and impact on clinical and economic outcomes
  
• Canadianizing an economic model comparing intensive atorvastatin treatment with standard simvastatin treatment based on data from the CARDS trial
  
• Cytomegalovirus (CMV): Biomarkers of congenital infection & disease and relationships therein
  
• Vaccination programs for pneumococcal disease in adults (≥50 years): Evidence on disease burden and unmet needs
  
• Vaccination programs for pneumococcal disease in the pediatric population: Evidence on disease burden and unmet needs
  
• Pneumococcal vaccine development in the post-Prevnar era: key issues in epidemiology and economic modeling
  
• Glaucoma (IOP) treatment in Canada
  
• HPV Vaccination
  
• Hip fracture
  
• Reimbursement and J-Code incentives for pharmacological stress test drugs (adenosine, dipyridamole, dobutamine) in the US
  
• DPP-4 inhibitors for diabetes
  
• Costs of short and long term disability in Type II diabetes, in particular relating to poor glycemic control, from the perspective of 3rd party payers (i.e., insurers, employers)
  
• The burden of Major Depressive Disorder (MDD)
  
• Health and economic outcome measures (number needed-to-treat and cost per quality adjusted life year) for medical interventions in Canada and the US
  
• Osteoarthritis and rheumatoid arthritis in Canada
  
• Pharmacoeconomic Assessment of medication for treatment of ulcers and gastroesophageal reflux disease (GERD)
  
• Comparison of NSAID + PPI treatment versus COX-2 selective inhibitors on NSAID-related gastrointestinal events
  
• Status of Paget's Disease, treatments and current practice in Canada
  
• Vitamin D and osteoporosis
  
• Marketing of pharmaceutical products in the 1980s and 1990s
  
• Sarcopenia and cachexia: burden of illness and management patterns
  
• Congestive heart failure (CHF) in Ontario and Quebec
  
• Rates of nausea & vomiting and sexual dysfunction with SSRI & SNRI antidepressant use, their impact on compliance, and the effect of compliance on depression outcomes
  
• Cost-of-illness of acromegaly and associated co-morbidities
  
• Acromegaly and associated comorbidities
  
• Haloperidol treatment for schizophrenia
• Positioning of omalizumab relative to other biologics in Canada
  
• Risperidone treatment for schizophrenia
  
• Oral inflammation and human systemic disease [Full Text]
  
• Drivers of health care cost growth in the US
  
• The treatment of dyslipidemia
  
• The limitations of statin therapy in the treatment of hypercholesterolemia
  
• Prostate cancer treatment in Canada: current status and research investment
  
• Salmon calcitonin nasal spray (Miacalcin) for osteoporosis
  
• Economic and quality of life outcomes in renal and oncology-related anemia
  
• The Science Behind Colgate Total
  
• Deep vein thrombosis treatment and the market for non-pharmacological approaches
  
• Managing escalating pharmaceutical costs: challenges facing pharmacy services
  
• Economic evaluation and quality of life in organ transplantation
  
• New approaches to therapeutic intervention in cardiac hypertrophy
  
• Forces influencing inpatient hospital costs in the United States
  
• The role of Triclosan/Copolymer dentifrice in the prevention and control of periodontal disease

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Patient Information & Educational Materials (for example…)

Harvard Continuing Medical Education for Dental Health Professionals
Quarterly continuing education test material based on oral health research, 1996 to present

Manuel de transplantation pulmonaire/Lung transplantation manual
Multidisciplinary bilingual informational package for patients undergoing lung transplantation

Major published clinical trials in the treatment of rheumatoid arthritis and osteoarthritis
Structured multimedia summaries of pivotal studies in rheumatology for CME

Accreditation course modules
Review, evaluation of and report on 13 modules used for basic biomedical and pharmacology training of pharmaceutical sales and marketing personnel

Biomedical course modules
A series of multimedia materials prepared for basic biomedical training of pharmaceutical personnel

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